Research progress of chimeric antigen receptor T cells in the treatment of primary liver cancer / 基础医学与临床

ABSTRACT

CAR-T technology as a kind of immunotherapy, from the earliest generation of the first to the current fourth generation, its cytotoxic, anti-tumor immune effect greatly enhanced, but also challenged by safety issues.It shows a certain advantage in the therapy of Hepatocellular carcinoma. It indicates that the era of precise individual-ized liver cancer treatment, immune therapy, especially CAR-T technology combined with surgery, radiotherapy and chemotherapy, local treatment and other comprehensive treatment will play a more powerful role.