Application of thromboelastography for patients with liver cirrhosis under liver resection / 临床麻醉学杂志

ABSTRACT

Objective To investigate the effect of thromboelastography (TEG) in guiding clinical transfusion in liver cirrhosis patients during operation.Methods Sixty liver cirrhosis patients who underwent liver resection under general anesthesia from April 5,2015 to October 30,2016 were selected in this study.Among them,there were male in 46 cases and female in 14 cases,ASA physical status Ⅱ or Ⅲ,Child-Pugh grade B or C.According to coagulation function,the patients were divided into thrombelastogram analysis group (group TEG,n =30) and empirical treatment group (group control,n =30).The coagulation time (R),the formation time (K),the maximum amplitude of thrombosis (Ma) and solidification angle (alpha value) were observed and recorded.According to the analysis results,choice type and quantity of infused blood was chosen.Results The bleeding volume in group TEG and blood transfusion (including suspended red blood cells,fresh frozen plasma,cryoprecipitate,platelet) were significantly reduced,compared with the group control (P＜0.05);the bleeding volume of 12,24 h in group TEG was significantly lower than that in group control (P＜0.05).Conclusion Thromboelastography can monitor the real-time blood coagulation function in patients,guide the perioperative blood transfusion and reduce the input of blood products during the surgery and postoperative abdominal bleeding occurrence,which has important application value in resection of liver cirrhosis in patients with liver cancer.