The comparison of the early cognitive function of elderly patients underwent sevoflurane static in-halation combined anesthesia and total intravenous anesthesia after total hip replacement / 临床外科杂志

ABSTRACT

Objective To compare the early cognitive function of elderly patients underwent sevoflurane static inhalation combined anesthesia and total intravenous anesthesia after total hip replace-ment.Methods A total of 80 cases with femoral neck fractures were randomly divided into two groups with 40 cases in each group.The A group was given sevoflurane static inhalation combined anesthesia and the B group was given total intravenous anesthesia.The cognitive function score of patients before and after anesthesia,the incidence of postoperative cognitive dysfunction(POCD)and the postoperative recovery were recorded and analyzed.Results The mini-mental state examination(MMSE)score at 2 h(23.08 ± 2.10)and 6 h(24.86 ± 1.51)after surgery in the A group were significantly higher than that at 2 h (21.34 ± 1.61)and 6 h(22.12 ± 1.56)in the B group.There were significant differences between the two groups(P<0.05).The incidence of POCD in the A group(20.0%)was significantly lower than that in the B group(32.5%).There were significant differences between the two groups(P<0.05).The MoCA score at 2 h(23.88 ± 1.32),6 h(24.56 ± 0.88)and 1 d(26.12 ± 1.03)after surgery in the A group were significantly higher than that at 2 h(21.78 ± 0.88),6 h(22.98 ± 1.21)and 1 d(24.48 ± 1.13)in the B group.There were significant differences between the two groups(P<0.05).Conclusion The ap-plication of sevoflurane static inhalation combined anesthesia can decrease the incidence of early POCD and effectively improve the cognitive ability of elderly patients after total hip replacement.