Comparative study on MSCT findings and the pathology of pancreatic neuroendocrine tumors / 中华内分泌外科杂志

ABSTRACT

Objective To study the multi-slice computed tomography (MSCT) features of pancreatic neuroendocrine tumors (PNET).Methods In the retrospective study,30 histologically verified pancreatic neuroendocrine tumors were incidentally detected with contrast enhanced MSCT.Various CT findings such as location,size,pattern,enhancement were analyzed.All tumors were graded as G1 to G3 according to WHO classification in 2010.Results There were 30 lesions in 30 patients with histologically confirmed PNET,including 16 lesions in G1,6 lesions in G2,and 8 lesions in G3.16 lesions were located in head of pancreas,8 lesions located in pancreatic body,and 6 lesions located in tail of pancreas.16 tumors were solid,3 tumors predominantly cystic,and 11 lesions solid and cystic.Calcification was observed in 6 cases.There was no significant difference in tumor location,size,solid or cystic,calcification among the different pathological grades of the tumor.CT values in patients with G1 PNETs in arterial,portal and delay phase were higher than those in patients with G3 PNETs (P＜0.05).Conclusion Dynamic enhancement CT may provide useful information to preoperative grading of PNET and tumors in a higher grade may show poorer enhancement.