Molecular mechanism for telomere-binding proteins in regulating mammalian spermatogenesis / 上海交通大学学报（医学版）

ABSTRACT

Telomere attachment to the nuclear envelope and telomere-led chromosomal movement allow proper homologous pairing in mammalian meiotic prophase I. However, the molecular mechanisms for telomere meiosis-specific functions remain to be elucidated. The present review introduced the structure basis for telomere attachment to the nuclear envelope, and revealed a new mechanism by which telomere functions in mammalian spermatogenesis.