Analysis of diagnosis and treatment for cervical cancer of stage Ⅰ A1 / 复旦学报（医学版）

ABSTRACT

Objective To evaluate the evolution of the effective and safe diagnostic and surgical approaches for patients with cervical cancer of stage Ⅰ A1 during ten years.Methods A retrospective cohort study of 721 cases diagnosed with cervical cancer of stage Ⅰ A1 from 2005 to 2014 was conducted by reviewing the archived medical records.Results Of patients with cervical cancer of stage Ⅰ A1,396 cases (54.9％) had no symptoms and follow-up materials.The transformation of treatment and curative effect were evaluated with Pearson chi square test,Spearman correlation analysis as well as Fisher's exact probability.Pathology of biopsy clarified the diagnosis for 82 cases (11.4 ％),and pathologic results of conization made the definite diagnosis for 640 cases (89.9 ％) (P＜0.01).Laparoscopy grew to be the main trend of surgical approach for cervical cancer of stage Ⅰ A1 instead of laparotomy from 2010 to 2014 compared with 2005 to 2009 (P＜0.01).Non-radical surgery became more popular to the cohort from 2010 to 2014 (P＜0.01).Thirty-five cases (4.9％) were lost to follow-up.There was no dead case and a case of recurrence.Conclusions Conization was very important to clarify the diagnosis for cervical cancer of stage Ⅰ A1.Laparoscopic hysterectomy was a safe and effective treatment for cervical cancer of stage Ⅰ A1 patients.