Consideration and Exploration on Pharmacokinetic Study of Traditional Chinese Medicine / 世界科学技术-中医药现代化

ABSTRACT

With the development of traditional Chinese medicine (TCM) modernization,the study of TCM is not only limited to clarify the chemical material basis in vitro,but also to further study the fate of active components contained in TCM in vivo as well as the interaction and effect among them.It is to say that the pharmacokinetic (PK) study of TCM is needed.The results of PK study of TCM are useful for investigating its mechanism of action,reasonable use of TCM in clinic and modernization of TCM.In this paper,some scientific issues,including the purpose and significance of PK study of TCM,its particularity,difficulty and commonly used research methods,were analyzed and summarized combining with research examples.The authors hoped that it would be helpful for the scholars and promote the development of PK study of TCM.