Laboratory Diagnosis and Analysis of Demodex from Patients with Blepharitis and Related Ocular Disease / 现代检验医学杂志

ABSTRACT

Objective To assist clinical diagnosis of Demodex blepharitis and other related ocular surface disease.Methods 42 cases were collected from the patients diagnosed of blepharitis,dry eye or blepharitis related keratoconjunctivitis (BKC) from the outpatient of the First Hospital of Xi'an City from April and July 2016.The eyelashes were pulled out and detected for the Demodex under microscopy after adding a drop of ethanol.Results 30 cases in 42 patients were detected for the Demodex (the positive rate was 71 ％),while only 1 case in 10 healthy volunteers was detected for the Demodex with the positive rate of 10 ％.The difference between the two groups was statistically significant (x2 =10.23,P＜ 0.01).Conclusion There is a high incidence rate of Demodex blepharitis.The early rapid laboratory diagnosis for Demodex blepharitis should be paid attention to and reinforced,in order to guide the timely and accurate treatment and avoid the occurrence and development of the Demodex related blepharitis,dry eye,BKC or other ocular complications.