Congenital defects of phagocyte number or function / 中华实用儿科临床杂志

ABSTRACT

Congenital defects of phagocyte number,function or both was categorized to the fifth classification from the international union of immunological societies expert committee for primary immunodeficiency 2015.Severe congenital neutropenia was the most fatal phagocyte number defect.Phagocyte functions included motility,chemotaxis,adhesion,phagocytosis and killing.Leukocyte adhesion deficiency and chronic granulomatous disease were the most common diseases.This article will describe pathogenesis,molecular,clinical,laboratory features and treatment and prognosis,to supporting clues for paediatrician's clinical operations.