A Case of penile Melanosis / 대한피부과학회지

ABSTRACT

Penile melanosis is a beniign macular hyperpigmentation of the penile shaft and/or glans. Clinically the lesions are irregular in outline and show variegated pigmentation. The main differential diagnostic problem is with acral levtiginous melanoma. A 28-year-old man was seen with slowly growing, asymptomatic, multifocal, and variegated hyperpigmented maculs on the glans penis of 28-year-duration. The post and family history were non-contributory. Hostogologic examination showed acanthosis and basal layer hyperpigrnentation but atypical melanocytes were not seen. Fontana-Masson stain showed increased melanin pigmentation with dendritic elongation of melanocytes in the basal layer of the epidermis. Little is known about the natural history and melnona risk of penile melanosis and we believe that a long-term follow-up is warranted. This patient showed no change during the follow-up period of 2 years and we will continue to monitor him long-term.