Study progress of diagnosis for asthma in preschool-aged children / 中华实用儿科临床杂志

ABSTRACT

Children under 6 years old are high-risk group for wheezing,and it is difficult but essential for these particular group to be diagnosed with asthma. In the past 30 years,researches based on asthma prediction models have been raised,but with no specific diagnostic criteria. Experts of childhood asthma in China had established empiri-cal diagnostic criteria since 1998 and optimized it continuously,but it was denied due to lack of further research of evi-dence-based medicine. Independent and operative diagnostic criteria was out of range since 2008,therefore diagnosis might be a great challenge for clinical physicians. Now,it is necessary to explore and establish diagnostic criteria based on evidence-based medicine as well as experience of experts. Scholars of childhood asthma in China have obtained 38 asthma-related parameters after massive search of related literatures,and obtained 5 parameters ultimately through Delphi method,single factor analysis and multi-factor regression analysis,and have valued them according to relevant intensity. The diagnostic criteria for cumulative integration of children under 6 years of age has been established initia-lly,which is still in the verification stage,but is expected to provide timely and accurate diagnosis for early childhood asthma.