Research of Correlation between Platelet Function and Count of Pregnancy / 实用妇产科杂志

ABSTRACT

Objective:To discuss the correlation between platelet count and thrombelastogram(TEG) parameters on pregnancy whose platelet count on the various levels,in order to find the intrinsic relations of platelet function and count,to provide the basis of the function evaluation of PLT during pregnancy and treatment.Methods:The PLT count,TEG parameters and coagulation function were tested in 200 pregnancy women from October 2014 to March 2016.Spearman test was used to analyze the correlation between the platelet count TEG parameters and coagulation function.Results:The TEG parameters which were positively correlatd with PLT count included MA(r =0.756,P ＜ 0.01),Angle (r =0.626,P ＜ 0.01),CI (r =0.635,P ＜ 0.01);The TEG parameters which were negatively correlatd with PLT count was K(r=-0.695,P ＜0.01);The TEG parameters which were not correlatd with PLT count included R、APTT、PT.In the mild lack of platelet group(PLT count 70 × 109/L-135 × 109/L) and the low value group(PLT count 135 × 109/L-200 × 109/L),platelet count was positive correlated with MA and Cl,ln the low value group and the high value group(PLT count ＞200 ×109/L),platelet count was positive correlated with Angle.In the mild lack of platelet group,the low value group and the high value group,platelet count was negatively correlated with K,In the severe lack of platelet group (PLT count 30 × 10 9/L-70 × 10 9/L),platelet count was negatively correlated with Fg.In the other group,there was no significant correlation between platelet count and TEG parameters、blood coagulation parameters.Conclusions:Platelet count was significantly correlated with MA,Angle and CI;But on the pregnancy with platelet count was extreme low value and high value,platelet count can not reflect the aggregation function,MA can more sensitively reflectthe platelet function.