Long-term Predictive Values of HPV Test Using Alone in Cervical Cancer Screening: A Metal Analysis / 实用妇产科杂志
Journal of Practical Obstetrics and Gynecology
; (12): 371-376, 2018.
Article
in Zh
| WPRIM
| ID: wpr-696703
Responsible library:
WPRO
ABSTRACT
Objective:
To further evaluate the long-term predictive value of HPV test in cervical cancer screening.Methods:
To search PubMed and Web of Science databases by computer.The studies conducted HPV-based screening program and followed up for more than 3 years were included.After data extraction,the risk of cervical intraepithelial neoplasia(CIN) grade Ⅱ or worse(CIN Ⅱ +),CIN gradeⅢ or worse(CIN Ⅲ +),and cervical cancer was evaluated through the pooled cumulative incidence and odds ratio(OR) values among women with different baseline test results.Results:
Finally,26 cohort studies were included.Compared to cytology negative,negative for HPV test was associated with significantly lower incidence of cervical diseases within 3 years (CIN Ⅱ +OR =0.500,P < 0.001;CIN Ⅲ+OR =0.377,P < 0.001;cervical cancerOR =0.546,P < 0.001).The 5-year pooled cumulative incidence of CIN Ⅱ +,CIN Ⅲ + and cervical cancer in HPV negative women was lower than 3-year detection rates in cytology negative women(CIN Ⅱ +0.47% vs 0.60%;CINⅢ +0.15% vs 0.20%;cervical cancer0.016% vs 0.020%),while the OR values had no significant difference.Conclusions:
We recommend that HPV test using alone can be considered as an alternative strategy for cervical cancer screening with five-year screening interval.
Full text:
1
Index:
WPRIM
Type of study:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Screening_studies
Language:
Zh
Journal:
Journal of Practical Obstetrics and Gynecology
Year:
2018
Type:
Article