The correlation between cartilage morphology and T2 value of MR and clinical manifestations in knee osteoarthritis / 实用放射学杂志

ABSTRACT

Objective To investigate the correlation between the MRI morphology scoring of cartilage injury,the changes of T2 value and clinical manifestations in knee osteoarthritis (OA).Methods Ten healthy volunteers and 65 patients with OA were enrolled.The patients were graded according to the Western Ontario and McMaster University Osteoarthritis Index (WOMAC).Knees of all research participants underwent MRI scanning of sagittal 3D-WATSc and T2 mapping.Patients were further divided into group OA1,group OA2 and group OA3 based on Whole-Organ Magnetic Resonance Imaging Score (WORMS).The correlation between the WORMS scores,T2 values of the knee cartilages and the clinical WOMAC scores was analyzed.Results The WORMS scores of the cartilages were positively correlated with the total WOMAC scores,pain scores,stiffness scores and activity scores,with the correlation coefficient of 0.806,0.690,0.493 and 0.817,respectively (P＜0.05).The T2 values of the cartilages had a positive correlation with the total WOMAC scores,pain scores,stiffness scores and activity scores,with the correlation coefficient of 0.501,0.384,0.357 and 0.512,respectively (P＜0.05).Conclusion WORMS as MRI semi-quantitative evaluation index and T2 values as MRI quantitative evaluation index could reflect clinical manifestations of patients with knee OA to some extent.