Imaging diagnosis of solitary plasmacytoma in bone / 实用放射学杂志

ABSTRACT

Objective To investigate the imaging findings of solitary plasmacytoma in bone(SPB)to improve the diagnostic accuracy. Methods The imaging data of 22 cases with SPB confirmed by pathology were reviewed retrospectively,including DR(n=15),CT (n=20)and MRI(n=11).8 patients were examined by DR,CT and MRI.Results The tumors were located at vertebrae(n=9),humerus (n=1),scapula(n=2),sternum(n=1),ilium(n=3),pubis(n=1),ribs(n=2),frontal bone(n=1)and mandible(n=2).The lesions showed as expansive growth and punched-out like bone destruction with well-defined margins on DR and CT.Soft tissue masses(n=7) or bony ridge(n=11)could be observed.No periosteal reaction was shown in any cases.One case was misdiagnosed as odontoma, which demonstrated as patchy high-density lesion in the mandible.The lesions were of same signal or slightly hyper-intensity on T1WI and hyper-intensity on T2WI and DWI compared with the muscle signal.There was soft tissue infiltration without obvious peritumoral edema.The lesions combined with bony ridge were shown as"mini brain"sign."Cuff sign"could be seen in 4 cases in the vertebrae. The tumors enhancement was obvious after injection of contrast agent.Conclusion The diagnosis of SPB is relatively difficult,and should be comprehensively analyzed by combining imaging features,clinical and laboratory examinations.