Correlation study between CT features of clear cell renal cell carcinoma whose diameter ≥7 cm and its Fuhrman grade / 实用放射学杂志

ABSTRACT

Objective To investigate the application value of CT features of clear cell renal cell carcinoma (CCRCC) whose diameter ≥ 7 cm in predicting its Fuhrman grade.Methods 53 patients with CCRCC confirmed by surgery and pathology were analyzed retrospectively,including 19 patients regarded as a low-grade (Grade Ⅰ and Grade Ⅱ) group,and other 34 ones as a high-grade (Grade Ⅲ and Grade Ⅳ) group.The CT features including necrosis,renal sinus involvement,shape,renal vein invasion,lymphnode metastasis,pseudo-capsule,blood vessels around the tumor and the boundary between the tumor and the perirenal fat were analyzed,and the differences in those CT features between two groups were analyzed with chi-square or Fisher exact test.Results The incidence of fuzzy boundary between the tumor and the perirenal fat in the high-grade group was higher than that in the low-grade group (x2 =6.129,P =0.013),however,the differences of the rest CT features between two groups were not statistically significant (P＞0.05).When the fuzzy boundary was used to predict the high-grade CCRCC,the sensitivity,specificity and accuracy was 61.8 ％,73.7 ％ and 66.0 ％,respectively.Conclusion When the diameter of the tumor ≥7 cm,only the fuzzy boundary between the tumor and the perirenal fat has certain value in predicting high-grade CCRCC.