Bone regeneration around dental implant with bone marrow mesenchymal stem cells sheet and platelet rich plasma / 实用口腔医学杂志
Journal of Practical Stomatology
;
(6): 206-210, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-697486
ABSTRACT
Objective:
To study the bone regeneration capacity of the BMSCs cell sheets combined with PRP used with dental implant.Methods:
BMSCs were isolated from young SD rats and induced to form cell sheets(BMSCs); PRP were prepared from the fresh blood of rats; PRP gel with BMSCs fragments(BMSCs + PRP) were injected into the space of dental implant of Ti and β-TCP. BMSCs, PRP and BMSCs + PRP with the implant were respectively transplanted into nude mice(n = 6). 8 weeks after transplantation bone regeneration were examined by Micro CT and hard tissue slicing.Results:
The group of BMSCs + PRP showed more new bone formation around implants with blood vessel than the group of BMSCs and PRP.Conclusion:
BMSCs sheets with PRP can improve the bone regeneration around dental implants.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Practical Stomatology
Year:
2018
Type:
Article
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