Clinical features and curative effect analysis of tuberculosis accompanied by HIV/AIDS compared with pure tuberculosis / 实用医学杂志

ABSTRACT

Objective To analyze the therapeutic effects and investigate the differences in clinical characteristics betweenpatients with tuberculosis complicated by HIV/AIDS and those withtuberculosis alone.Methods The data on 189 patients with pulmonary tuberculosis who had received treatment and follow-up from January 2011 to December 2011.According to the CD4+T level of ＞ or ＜ 200/μL,We divided 102 individuals into group A (CD4+ T ≤ 200/μL),and group B(CD4+T ＞ 200/μL).The rest 87 patients were assigned to group C.The clinical symptoms,laboratory examinations,manifestations of chest X-rays,and efficacy were respectively analyzed.Results As compared with groups B and C,in group A the clinical appearance was mainly systemic symptoms;and the positive rate of laboratory examinations was lower.The chest X-ray showed more diffusepatchy andblurring shadows,commonly in multiple lung fields,and less fiber strand and cavity formation.More diffusion in multiple lung fields was seen in group B than in group C.The total effective rate was lower in group A than in groups B and C,but after the course was extended for 3 months,the total effective rate was not significantly different compared with groups B and C.Conclusions Detection of CD4+T lymphocytesin patients with suspect HIV/AIDS complicated by tuberculosis has important significance in the early diagnosis and treatment and isolation.