The effect of BIS-guided propofol TCI in preventing adverse effect of carboprost tromethamine in puerperants undergoing caesarean section: a prospective, randomized controlled trial / 实用医学杂志
The Journal of Practical Medicine
;
(24): 124-127, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-697568
ABSTRACT
Objective To investigate whether BIS-guided (target-controlled infusion) propofol TCI can effectively prevent adverse effects of carboprost tromethamine in patients undergoing caesarean section.Methods Three hundred and fifty-four puerperants underwent spinal-epidural anesthesia were randomized into 3 groupsafter fetal childbirth,in the control group,normal saline was infused at a rate of 10 ml/h.BIS 85 group,propofol with the initial target plasma concentrations of 0.8 μg/ml by TCI,adjusted TCI concentration and maintained BIS 80-90.BIS 75 group,propofol with the initial target plasma concentrations of 1.2 μg/ml by TCI,adjusted TCI concentration and maintained BIS 70-80,both until the end of operation.tThe rate of nausea,vomiting,diarrhea,chest congestion and headache were compared among 3 groups.Results Compared with the control group,the incidence of chest congestion was significantly reduced in BIS 85 group (P =0.004).The incidence of nausea,vomiting and chest congestion were significantly reduced in BIS 75 group (P < 0.001,respectively).The puerperants in 2 BIS groups had no complaints of headache.Conclusion BIS-guided propofol TCI and maintaining BIS 70-80 can effectively prevent adverse effect of carboprost tromethamine in puerperants undergoing spinal-epidural anesthesia in caesarean section.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Controlled clinical trial
Language:
Chinese
Journal:
The Journal of Practical Medicine
Year:
2018
Type:
Article
Similar
MEDLINE
...
LILACS
LIS