Research progress on the relationship between ADSCs and immunomodulatory factors / 天津医药
Tianjin Medical Journal
;
(12): 109-112, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-697985
ABSTRACT
Mesenchymal stem cells (MSCs) are defined as undifferentiated cells that are capable of self renewal and functionally capable of differentiating into adipocytes, osteoblasts, chondrocytes, hepatocyte-like cells, myogenic-like cells, neuron-like cells, and islet-like cells. MSCs possess immunomodulatory properties according to secrete indoleamine-2, 3-dioxygenase (IDO) and prostaglandin E2 (PGE2) to play the role of immunomodulatory. Moreover, pre-stimulation of interferon-γ (IFN-γ) can promote the immunomodulatory function of MSCs. High abundance of MSCs found in adipose tissue makes it a very attractive source of adult stem cells. This article reviews the recent progress in the interaction between adipose derived mesenchymal stem cells (ADSCs) and three immunomodulatory factors.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Tianjin Medical Journal
Year:
2018
Type:
Article
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