Advances in Diagnosis and Treatment of Primary Sclerosing Cholangitis / 胃肠病学
Chinese Journal of Gastroenterology
;
(12): 271-276, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-698187
ABSTRACT
Primary sclerosing cholangitis (PSC)is a chronic cholestatic liver disease characterized by inflammation, fibrosis,and stricture of the intra- and/ or extrahepatic bile ducts. PSC is frequently insidious onset,but may aggravate progressively and ultimately leading to biliary cirrhosis and eventually hepatic failure. Most of the PSC patients are associated with inflammatory bowel disease,and the risk of hepatobiliary malignancy especially cholangiocarcinoma increases significantly. So far,the mechanism of PSC is not clearly known and lacking effective medical therapy. This article provides a comprehensive review on advances in diagnosis and treatment of PSC,including the consensus on imaging diagnosis,prognostic stratification and new drugs in ongoing trials.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
Language:
Chinese
Journal:
Chinese Journal of Gastroenterology
Year:
2018
Type:
Article
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