Effect of Metal Stents Combined With Nasobiliary Drainage on Preventing post-ERCP Cholangitis in Patients With Cholangiocarcinoma / 胃肠病学
Chinese Journal of Gastroenterology
;
(12): 351-355, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-698201
ABSTRACT
Background:
Cholangitis is common in patients with advanced cholangiocarcinoma after endoscopic metal biliary endoprothesis (EMBE).Aims:
To explore the effect of EMBE combined with endoscopic nasobiliary drainage (ENBD)on preventing post-ERCP cholangitis in patients with cholangiocarcinoma.Methods:
A total of 263 advanced cholangiocarcinoma patients underwent EMBE were enrolled and divided into EMBE group and EMBE plus ENBD group. Incidence of post-ERCP cholangitis,adverse event rate and hospital stay were evaluated between the two groups.Results:
Compared with EMBE group,incidence of post-ERCP cholangitis (2. 3% vs. 10. 8%,P =0. 032 )and hospital stay [(4. 68 ± 1. 43)days vs. (5. 18 ± 1. 45 )days,P =0. 011 ]were significantly lower in EMBE plus ENBD group, especially in patients with hilar cholangiocarcinoma [incidence of post-ERCP cholangitis3. 5% vs. 15. 0%,P=0. 045;hospital stay(5. 18 ± 1. 44)days vs. (5. 68 ± 1. 39)days,P=0. 033]. C-reactive protein,white blood cell count, percentage of neutrophil after 3,24,72 hours were significantly decreased in EMBE plus ENBD group than in EMBE group (P<0. 05). No significant difference in procedure-related adverse event was found between the two groups (P>0. 05).Conclusions:
The combination of EMBE with ENBD is safe and effective in preventing post-ERCP cholangitis,especially in patients with hilar cholangiocarcinoma.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Gastroenterology
Year:
2018
Type:
Article
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