A modified working tube can reduce bone cement Ieakage in the treatment of osteoporotic vertebraI compression fracture / 中国组织工程研究

ABSTRACT

BACKGROUND: Vertebroplasty is an effective treatment for osteoporotic vertebral compression fractures (OVCF), but it is nagged by bone cement leakage. OBJECTIVE: To summarize the clinical outcome of modified self-making working tube in percutaneous vertebroplasty (PVP) for treatment of thoracolumbar OVCF. METHODS: Modified PVP working tube was designed to have a lateral gap at the sleeve tail, which could control the cement diffuse direction though rotating the working tube. Totally 121 thoracolumbar OVCF patients were enrolled, including 49 males and 72 females, aged 62-90 years, and then divided into two groups 59 patients were treated with modified PVP in test group, and the other 62 patients experienced conventional PVP in control group. In the test group, a lateral gap instead of the conventional gap at the sleeve tail was made to control the direction of bone cement injection by rotating the sleeve. The visual analogue scale scores were compared before and after operation; radiographic examination was performed to detect bone cement leakage at 1 day postoperatively. RESULTS AND CONCLUSION: There were significant differences between the preoperative and postoperative visual analogue scale scores in the two groups (P < 0.05), but there was no significant difference between the two groups. There were 3 cases of bone cement leakage in the test group and 10 cases of bone cement leakage in the control group. Modified PVP working tube had significant lower rate of bone cement leakage than traditional PVP(14.9% vs.4.6%,P<0.05).Therefore,the modified PVP working tube is an effective tool to decrease the incidence of bone cement leakage in the treatment of thoracolumbar OVCF.