Protective effects of probiotics on the cell membrane in different tissues of rats after treadmill exercise / 中国组织工程研究
Chinese Journal of Tissue Engineering Research
;
(53): 1877-1882, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-698629
ABSTRACT
BACKGROUND:
Changes in the immune function of different tissues after long-time exhaustive exercise stress and probiotics intervention are still unclear.OBJECTIVE:
To observe the morphological changes and cell membrane protective effects of different tissues and organs in rats after exhaustive exercise and probiotics intervention.METHODS:
Forty Sprague-Dawley male rats were randomly allocated into quiet control group, exercise control group, quiet administration group and exercise administration group. Rats in the exercise control and exercise administration groups underwent 6 weeks of exhaustive training, at a speed of 19.3 m/min, slope of 5o, once daily, 6 days weekly. Rats in the quiet administration and exercise administration groups were given 107CFU/mL probiotics via gavage,10.0 mL/(kg?d).The histopathological changes were observed under light microscope and Na+/K+-ATPase, Ca2+/Mg2+-ATPase and T-ATPase in the liver, intestine and stomach were tested after 6 weeks of training. RESULTS ANDCONCLUSION:
After exhaustive exercise, the liver, stomach and intestinal tissue presented with structure disorders, swelling and inflammatory cell infiltration and an decrease in the activity of Na+/K+-ATPase, Ca2+/Mg2+-ATPase and T-ATPase. After probiotic solution administrated, the structure of liver, stomach and intestine arranged closely and clearly, with no obvious congestion and edema. However, there were a few inflammatory cells and slight ulcers, and the activities of Na+/K+-ATPase, Ca2+/Mg2+-ATPase and T-ATPase were increased. These findings show that probiotic solution can protect the liver, stomach and intestinal tissue from injury caused by long-time exhaustive exercise, and maintain the integrity and fluidity of cell membrane by increasing Na+/K+-ATPase, Ca2+/Mg2+-ATPase and T-ATPase activities.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Tissue Engineering Research
Year:
2018
Type:
Article
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