Analysis of the effectiveness of synchronized nasal intermittent positive pressure ventilation for neonatal respiratory failure / 中国小儿急救医学

ABSTRACT

Objective To investigate the clinical effect of synchronized nasal intermittent positive pressure ventilation (SNIPPV) in the treatment of neonatal respiratory failure. Methods The clinical data of 52 neonates with respiratory failure treated in our hospital from January 2016 to January 2018 were retrospec-tively analyzed. According to the different treatment methods,they were divided into observation group and control group,26 cases in each group. The children in the observation group were treated with SNIPPV,while those in the control group were treated with synchronized intermittent positive pressure ventilation (SIPPV). Clinical efficacy,changes of blood gas analysis results before and after treatment,oxygen consumption time and hospital stay,and complications were compared between the two groups. Results The respiratory rate and heart rate of the two groups improved after treatment,but there were no significant differences between the two groups(P＞0. 05,respectively). The total effective rate of the observation group was 88. 5%,while that of the control group was 92. 3%,there was no significant difference between the two groups(χ2=0. 221, P＞0. 05). The pH,PaO2,PaCO2and oxygen saturation levels of 24 h after treatment in two groups were im-proved (P＜0. 05,respectively),but there were no significant differences between the two groups (P＞0. 05, respectively). Compared with the control group,the oxygen consumption time and hospitalization time of the observation group were significantly shorter, and the differences were statistically significant ( P ＜0. 05, respectively). And the observation group had fewer complications of ventilator associated pneumonia. Conclusion The effect of SNIPPV in the treatment of neonatal respiratory failure is significant. It could shorten the time of oxygen consumption and hospitalization and reduce the complications. It is worth populari-zing SNIPPV mode assisted ventilation.