Clinical study of serum NGAL and CysC levels in patients with morning hypertension / 心血管康复医学杂志
Chinese Journal of cardiovascular Rehabilitation Medicine
;
(6): 9-11, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-699331
ABSTRACT
Objective:
To measure serum levels of neutrophil gelatinase associated lipocalin (NGAL) and cystatin C (CysC) in patients with morning hypertension (MH) and explore their clinical value.Methods:
A total of 120 outpatients or inpatients with essential hypertension (EH) were selected from our department of cardiology. According to MH definition, they were divided into MH group (n=62) and non-MH group (n=58). Levels of serum NGAL and CysC, blood lipids and blood glucose were measured and compared between two groups.Results:
There were no significant difference in levels of blood lipids, blood glucose etc. between two groups, P>0. 05 all; compared with non-MH group, there were significant rise in serum levels of NGAL [(47. 50±3. 15) μg/L vs. (156. 87±18. 56) μg/L]and CysC [(0. 68±0. 16) mg/L vs. (1. 26±0. 86) mg/L]in MH group, P=0. 001 both.Conclusion:
Serum levels of NGAL and CysC in MH patients are significantly higher than those of non-MH patients, which is of great significance for diagnosing early renal dysfunction in MH patients. Therefore, management of morning blood pressure should be strengthened in clinic.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of cardiovascular Rehabilitation Medicine
Year:
2018
Type:
Article
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