Correlation between heart rate variability and severity of coronary artery lesion in patients with coro -nary heart disease / 心血管康复医学杂志
Chinese Journal of cardiovascular Rehabilitation Medicine
;
(6): 268-271, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-699400
ABSTRACT
Objective:
To study correlation between heart rate variability (HRV) and severity of coronary artery le-sion in patients with coronary heart disease (CHD) and its significance .Methods:
A total of 171 CHD inpatients from our department of cardiology were selected .All CHD patients were diagnosed by coronary angiography or cor- onary CT .Severity of coronary artery lesion was judged by Gensini scoring system .According to coronary stenotic degree ,patients were divided into coronary no stenosis group (n=30) ,mild group (stenosis<50%,n=51) ,medi-um group (stenosis 50% ~75%,n=46) and severe group (stenosis>75%,n=44).The 24h ambulatory ECG moni-toring was performed in all patients ,HRV indexes were compared among all groups and their correlation with sever-ity of coronary lesion degree were analyzed .Results:
There were significant difference in standard deviation of nor-mal to normal RR intervals calculated over the 24 h period (SDNN) ,standard deviation of normal to normal RR in-tervals in all 5 min segments of the entire recording (SDANN) ,root-mean square of differences between successive normal to normal intervals (rMSSD) and adjacent normal RR interval difference > 50ms stroke accounted for a per-centage of 24h total RR interval (PNN50) among four groups ,and HRV indexes significantly reduced along with coronary lesion aggravated , P<0.05 or <0.01. Multi-factor Logistic regression analysis indicated that HRV inde-xes were independent risk factors for coronary artery lesion aggravation (OR=1.359~3.254 ,P<0.05 or <0.01). Spearman correlation analysis indicated that SDNN ,SDANN ,rMSSD and PNN50 were significant inversely correla-ted with Gensini score (r= -0.510~ -0.271 ,P<0.05 all).Conclusion:
HRV possesses certain clinical application value assessing coronary lesion severity in CHD patients .
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Risk factors
Language:
Chinese
Journal:
Chinese Journal of cardiovascular Rehabilitation Medicine
Year:
2018
Type:
Article
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