Comparison of implantable collamer lens implantation and FS-LASIK for moderatetohigh myopia / 眼科新进展

ABSTRACT

Objective To evaluate and compare the primary clinical efficacy in high myopia patients undergoing implantable collamer lens (ICL) implantation or femtosecond laser-LASIK (FS-LASIK).Methods Totally 73 patients with myopia from August 2016 to March 2017 in our hospital were collected and divided into ICL group(35 patients with 69 eyes) who receiving ICL implantation and LASIK group (38 patients with 76 eyes) who underwent FS-LASIK.There was no significant difference in gender composition and age between the two groups (both P ＞ 0.05).In addition,there was no significant difference in contrast sensitivity function (CSF) and glare CSF (GCSF) between the two groups before operation (both P ＞ 0.05).After 6 months of follow-up,the patient's uncorrected visual acuity,best corrected visual acuity and equivalent spherical degree were detected,and efficacy index and safety index were calculated.Meanwhile,CSF and GCSF examination were performed,followed by the observation of the occurrence of complications.Results There was no significant difference in the uncorrected visual acuity and best corrected visual acuity between the two groups before surgery (all P ＞ 0.05).The preoperative spherical equivalent in the ICL group was -4.000 to-12.00 (-8.86 ±3.70)D,and-4.00 to-11.75 (-8.51 ±4.20)D in the LASIK group,with no statistically significant difference (P ＞ 0.05).There was no significant difference in the uncorrected visual acuity,best corrected visual acuity and spherical equivalent between the two groups after surgery (all P ＞ 0.05).The efficacy coefficient and safety index of the ICL group were better than those in the LASIK group after 6 months,and the differences were statistically significant (all P ＜ 0.05).The CSF in the ICL group was at 1.5 c · d-1,3.0 c · d-1,6.0 c · d 1,12.0 c · d-1,and 18.0 c · d-1 after surgery,which was superior to the LASIK group,and the differences were statistically significant (all P ＜ 0.05).The GCSF in the ICL group was at 1.5 c · d-1,3.0 c · d-1,6.0 c · d-1 and 18.0 c · d-1 after surgery,which was superior to the LASIK group,and the differences were statistically significant (all P ＜ 0.05).Four hours after operation,there were 4 patients (7 eyes) with increased intraocular pressure,which were controlled by anterior chamber puncture,but no lens opacity presented.Conclusion Both ICL and FS-LASIK can effectively correct moderateto highmyopia,but ICL is better than FS-LASIK at the effectiveness index,the safety index,CSF and GCSF.