Clinical and pathological features of corneal neoplasm / 眼科新进展

ABSTRACT

Objective To analyze the clinical features and pathological classification of corneal neoplasms.Methods The clinical data of 135 patients (136 eyes) of corneal neoplasm between January 2002 and June 2016 in Tianjin Eye Hospital were reviewed retrospectively,and the pathological features were analyzed.Results Together 118 patients (87.41％) with benign neoplasms were found,including 100 patients with corneal dermoid neoplasms,8 patients with epithelium cell proliferation,6 patients with corneal nevus pigmentation,2 patients with squamous papilloma,1 patient with epithelial cyst,1 patient with proliferation of granulation tissue.And 17 patients (12.59％)with premalignant or malignant neoplasms were found,including 5 patients with actinic keratosis,5 patients with squamous cell carcinoma,4 patients with carcinoma in situ,3patients with atypical hyperplasia.In 5 cases of squamous cell carcinoma patients,there were 2 cases of patients with papillary squamous cell carcinoma and 3 with invasive squamous cell carcinoma.The incidence of benign corneal neoplasms was highest in patients aged 0 to 17 years,and the prevalence of precancerous lesions and malignancies was highest in patients over 60 years of age.Conclusion In patients with corneal neoplasm,corneal dermoid neoplasm is the most common benign tumor of the cornea,and actinic keratosis and squamous cell carcinoma are the most common corneal precancerous lesions and malignancies accordingly in our study.