Studies on pathogenesis and gene therapy of red-green color blindness / 中华实验眼科杂志
Chinese Journal of Experimental Ophthalmology
;
(12): 549-552, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-699779
ABSTRACT
Red-green color blindness is the most common form of colour blindness.Traditional treatment options such as tinted lenses do not cure color blindness completely.With the rapid development of gene diagnostic and managing technology,gene therapy has been applied to inherited retinal diseases widely.The genetic treatment of Leber congenital amaurosis has entered clinical trail and shown the remarkable success in safety and efficacy.In recent years,gene therapy has finally reached a milestone to convert adult male squirrel monkeys with red-green color blindness to trichromats.It heralds the bright prospects of gene therapy applied in human red green color blindness.This article briefly reviewed the recent preclinical research achievements of pathogenesis and gene therapy for redgreen color blindnes.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Etiology study
Language:
Chinese
Journal:
Chinese Journal of Experimental Ophthalmology
Year:
2018
Type:
Article
Similar
MEDLINE
...
LILACS
LIS