Prognostic factors related to recurrence after low- dose tacrolimus treatment in patients with myasthenia gravis / 中国医师进修杂志
Chinese Journal of Postgraduates of Medicine
;
(36): 823-825, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-700297
ABSTRACT
Objective To identify the 2- year recurrence- related factors in patients with myasthenia gravis (MG) after treatment of low-dose tacrolimus. Methods The clinical data of 100 MG patients treated with low- dose tacrolimus from February 2011 to February 2016 were retrospectively analyzed. All patients were followed up at least 2 years, and the risk factors affecting the recurrence of MG patients were analyzed. Results At the end of follow-up, there were 49 cases who had recurrence, and the recurrence rate was 44.5% (49 / 110). Logistic regression analysis result showed that reducing dosage or withdrawal, MG crisis and diabetes mellitus were the independent risk factors for recurrence of MG patients (OR = 134.113, 8.850 and 6.652; P < 0.01 or <0.05). Conclusions The rate of recurrence with low- dose tacrolimus treatment in patients with MG during 2 years is higher. Reducing dosage or withdrawal should be avoided, especially in patients with a history of MG crisis. Patients with diabetics mellitus need to control blood glucose stability to avoid recurrence.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
/
Risk factors
Language:
Chinese
Journal:
Chinese Journal of Postgraduates of Medicine
Year:
2018
Type:
Article
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