Research progress of microRNA-7 in endocrine malignant tumors / 医学研究生学报

ABSTRACT

MicroRNA(miRNA)is a class of non-coding,endogenous RNA molecules.It has been confirmed in many studies that miRNA has aberrant expression in human tumors,which is related to the occurrence,progression and the response to treatment of various human tumors.MicroRNA-7(miR-7)is an important member of the miRNA family.Recent studies have reported that miR-7 is closely related to the occurrence,development,treatment and prognosis of endocrine malignant tumors such as thyroid cancer and pan -creatic cancer,indicating that it may serve as a potential molecular target for biological treatment of endocrine malignancies.The re-search progression in the relationship between miR-7 and thyroid cancer,as well as other endocrine malignant tumors are reviewed in this paper.