Research progress of calcium oxalate stones / 医学研究生学报

ABSTRACT

Calcium oxalate stones are the main components of the urinary calculi .The reasons for the formation of calcium ox-alate stones, the methods of researching calcium oxalate stones in vivo and in vitro , the relationship between renal tubular epithelial cell injury and calcium oxalate stones , the relationship between renal calcium oxalate stones and oxidative stress , the source of reactive oxygen species in renal calcium oxalate stones and renal calcium oxalate stones with antioxidant therapy were summarized in this paper . A new viewpoint was also provided for the treatment of renal calcium oxalate stones .Oxalate degradation enzymes can degrade oxalic acid into hydrogen peroxide and carbon dioxide to reduce the absorption of oxalic acid in the gastrointestinal and then limit the formation of calcium oxalate stones.Therefore, it will become a research hotspot in the future to screen oxalate degradation enzymes with high effi -ciency and low toxicity for calcium oxalate stones prevention .