Serum Peroxiredoxin 3 in Early Pregnant Women / 医学研究杂志

ABSTRACT

Objective To investigate the role of peroxiredoxin 3 (PRX3) in early pregnancy.Methods We collected serum and villus tissues from ninety patients at first trimester.Enzyme-linked immunosorbent assay,real-time PCR,and Western Blotting were applied to examine the PRX3 level in above samples.Results The serum PRX3 in pregnant women was significantly higher than in non -pregnant controls.The expression of PRX3 in villus tissues was increased with gestational progression.Conclusion The oxidative stress was increased in pregnant women.PRX2 plays an active role in antioxidant defense of villus tissues.