Analysis of Risk Factors for Heart Failure in Patients with Non-dialysis Chronic Renal Failure / 医学研究杂志

ABSTRACT

Objective To investigate the risk factors of heart failure in patients with non-dialysis chronic renal failure,to provide a reference for the prevention and treatment of heart failure.Methods A total of 289 patients in Renmin Hospital of Wuhan University from January 2015 to January 2017 were enrolled in this retrospective study.They were divided into two groups according to the occurrence of heart failure General information,relevant auxili-ary examination and laboratory tests were collected to analyze.Multivariate Logistic regression was used to analyze the risk factors of heart failure in patients with chronic renal failure.Results Univa-riate analysis showed that diabetes,blood pressure,anemia,myocardial damage,albumin,renal function,myocardial hypertrophy,pericardial effusion in the two groups were statistically significant(P ＜ 0.05).Logistic regression analysis showed that diabetes (OR =2.308,P =0.002),hypertension (OR =2.464,P =0.000),elevated creatine kinase (OR =3.065,P =0.000),hypoalbuminaemia (OR =0.845,P =0.000),hypocalcemia (OR =0.062,P =0.000),hyperphosphatemia (OR =2.868,P =0.000) were independently associated with heart failure in patients of chronic renal failure.Conclusion Diabetes mellitus,hypertension,myocardial in-jury,low albumin,imbalance of calcium-phosphorus metabolism are risk factors for heart failure.Paying attention to these factors is of great significance to the prevention and treatment of heart failure.