Anaysis of 268 Cases of Phlegm-dampness Syndrome of PCOS with Hyperandrogenism / 医学研究杂志

ABSTRACT

Objective Through the collection and analysis of clinical features and biochemical indices data got from 436 women who were diagnosed as phlegm-dampness syndrome of PCOS,in order to provide the reference for the personalized treatment for disease and prevention of long-term complication.Methods We collected 436 cases of patients diagnosed with phlegm-dampness syndrome of PCOS and 62 cases of control group from December 2014 to August 2017.We analysied and compared of three groups of clinical and biochemical indicators.Results The incidence of hirsutism,acanthosis nigricans and excessive fat of phlegm-dampness syndrome of PCOS + HA subgroup were higher than phlegm-dampness syndrome of PCOS + non-HA subgroup(P ＜ 0.05).The LH and LH/FSH of of phlegm-dampness syndrome of PCOS + HA subgroup were higher.The level of FSH and SHBG was lower than phlegm-dampness syndrome of PCOS + non-HA subgroup and the control group(P ＜ 0.05).The TC,TG and LDL of phlegm-dampness syndrome of PCOS + HA subgroup were higher than phlegm-dampness syndrome of PCOS + non-HA subgroup and the control group(P ＜ 0.05).The FPG,FINS and HOMA-IR of phlegm-dampness syndrome of PCOS + HA subgroup is higher than phlegm-dampness syndrome of PCOS +non-HA subgroup and the control group(P ＜ 0.05).Conclusion The patients with phlegm-dampness syndrome of PCOS + HA have higher incidence of hirsutism,acanthosis nigricans and excessive fat.The patients with phlegm-dampness syndrome of PCOS + HA have serious sex hormone metabolic disorders.The patients with phlegm-dampness syndrome of PCOS + HA have serious glucolipid metabolic disorders.