Research progress on glucose-regulated protein 78 in drug resistance and targeted therapy for cancer / 中国癌症杂志
China Oncology
;
(12): 156-160, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-701068
ABSTRACT
Glucose-regulated protein 78 (GRP78) plays an important role in the development of drug resistance in cancer, and GRP78 targeted therapy has become a hotspot of cancer research. In this article, we briefly introduce GRP78, review the research progress on the roles of GRP78 in drug resistance to cancer therapies, including chemotherapy, endocrine therapy and targeted therapy, and the mechanisms of resistance. The progress on GRP78 targeted therapy for cancer is also summarized.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Oncology
Year:
2018
Type:
Article
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