Effect of SerpinE2 on metabolism of extracellular matrix / 中国病理生理杂志
Chinese Journal of Pathophysiology
; (12): 173-177, 2018.
Article
in Zh
| WPRIM
| ID: wpr-701097
Responsible library:
WPRO
ABSTRACT
Serpin peptidase inhibitor clade E member 2(SerpinE2),a member of serine peptidase inhibitor super family,regulates multiple serine proteases.Extracellular matrix(ECM)plays an important role in stem cell differen-tiation,signal transduction,tumor metastasis,osteoarthritis physiological and pathological processes and so on.SerpinE2 regulates the protein of extracellular matrix by serine protease system and matrix metalloproteinase(MMP)system.In this paper,we elaborate the effect of SerpinE2 on metabolism of extracellular matrix,and it will provide new ideas to find new therapeutic targets.
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WPRIM
Language:
Zh
Journal:
Chinese Journal of Pathophysiology
Year:
2018
Type:
Article