Effect of pidotimod in the treatment of pediatric asthma / 中国基层医药

ABSTRACT

Objective To study the effect of pidotimod in the treatment of children with asthma.Methods 100 children with asthma were selected and randomly divided into control group and observation group,50 cases in each group.The control group received routine treatment,the observation group was given pidotimod on the basis of routine treatment.The asthma control effects,symptoms remission time,hospitalization time,pulmonary function index,the incidence rate of adverse reactions were compared between the two groups.Results The total effective rate of asthma control in the observation group (96％) was significantly higher than that in the control group (P ＜0.05).The cough,expectoration,shortness of breath,wheezing and other symptoms remission time and hospitalization time in the observation group were significantly shorter than those in the control group (all P ＜ 0.05).After treatment,FEV1,FEV1/FVC％,pulmonary ventilation function indices of the two groups were significantly increased (all P ＜ 0.05),and after treatment,the pulmonary function indices of the observation group were significantly higher than those of the control group (all P ＜ 0.05).The incidence rate of adverse reaction of the observation group was 8％,which of the control group was 6％,the difference between the two groups was not statistically significant (P ＞ 0.05).Conclusion Pidotimod in the treatment of children with asthma can effectively improve the asthma control effect,promote the alleviation of clinical symptoms,improve the pulmonary ventilation function,and with less adverse reactions,it is safe and reliable.