Comparison of the curative effects of laparoscopic surgery and traditional open surgery in the treatment of patients with stage Ⅰendometrial cancer and the influence on prognosis and quality of life / 中国基层医药

ABSTRACT

Objective To compare the curative effect of laparoscopic surgery and traditional open surgery in the treatment of patients with stage Ⅰ endometrial cancer and the influence on prognosis and quality of life . Methods 90 patients with stageⅠ endometrial cancer in the First People's Hospital of Xiangshan County from January 2010 to May 2011 were selected.According to the surgical method ,the patients were divided into study group and control group ,with 45 cases in each group .The patients in the study group were treated with laparoscopic surgery . The patients in the control group were treated with traditional open surgery .The surgery -related indicators , the prognosis and quality of life of the endometrial cancer patients in the two groups were compared and analyzed . Results Compared with the control group, the blood loss, operative time, flatus time, postoperative independent ambulation time,indwelling catheter time , and the average length of hospital stay of the study group were reduced significantly(t=97.58,17.06,9.51,8.24,12.16,8.09,all P<0.01).The incidence rate of complication in the study group was 13.33％,which was significantly lower than 31.11％ in the control group(χ2 =4.11,P<0.05). There were no statistically significant differences in the 5-year survival rate and local recurrence rate between the two groups (77.78％ vs.88.89％,35.55％ vs.26.67％,χ2 =2.00,0.58,all P>0.05).Compared with the control group,the scores of quality of life,included physiology,physiological functions,physical illness,general health, energy,social function,role emotional,and mental health in the study group were increased significantly (t=15.85, 11.17,13.86,22.47,15.20,11.32,10.78,20.67,all P<0.01).Conclusion Compared with traditional open surgery,laparoscopic surgery has a positive role in improving prognosis and quality of life of patients with stage Ⅰendometrial cancer .