Risk factors of long term mortality in elderly patients age over 75 years old with ST-segment elevation myocardial infarction after primary percutaneous coronary intervention / 中国介入心脏病学杂志

ABSTRACT

Objective To investigate the risk factors of short-term and long-term mortality in elderly patients with ST-segment elevation myocardial infarction(STEMI) after primary percutaneous coronary intervention(PPCI).Methods From Sept. 2011 to Jan. 2014, there were 27397 PCI cases performedin the Fuwai Hospital. 108 consecutive patients(0.39％) who aged over 75 diagnosed as acute myocardial infarction and underwent PCI were enrolled into this study. Cox proportional hazards model was used to analysis the risk factors of mortality during follow up.Results In the study population, 5 patients (4.63％) died during in-hospital stay, 7 patients(6.5％) died within 30 days after PPCI and 17 patients (15.7％)died during follow up[averaged follow up duration was (51.17±17.75) months] . Independent risk factors of 1-year mortality included female(HR 5.482, 95％CI1.099-27.333,P=0.038) and cardiac shock(HR 11.283, 95％CI 2.841-44.805,P=0.001). Stent implantation was found to be a protective factor(HR 0.173, 95％CI 0.032-0.943,P=0.043). Independent risk factors of long-term mortality included age(HR 1.146,95％CI 1.010-1.300,P=0.034)and cardiac shock(HR 4.928, 95％ CI1.718-14.130, P=0.003).Conclusions Old age, female, low LVEF, cardic shock and not having stent implantation were independent risk factors for mortality in elderly STEMI patients(≥75 years) who underwent primary PCI.