Research progress of mechanism of anti-NMDA-receptor antibodies in NPSLE / 中国免疫学杂志
Chinese Journal of Immunology
;
(12): 137-140,143, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-702689
ABSTRACT
Systemic lupus erythematosus (SLE)is an autoimmune disease,involving multiple organs and systems,and it is defined as neuropsychiatric systemic lupus erythematosus (NPSLE) when neuropsychiatric symptoms appear.The N-methyl-D-aspartate (NMDA) receptor is a kind of membrane-spanning ion channels' glutamate receptors,which mainly contains NR1 subunit and NR2 subunit.In recent years,the role of anti-NMDA-receptor antibodies in the pathogenesis of NPSLE has become a research hotspot,especially for anti-NR2 antibody.Therefore we review the research progress of the mechanism of the anti-NMDA-receptor antibodies in NPSLE in this paper.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Immunology
Year:
2018
Type:
Article
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