Clinical value comparison of two kinds of preoperative biopsy protocols on patients with gastric cancer for early stage underwent ESD / 中国内镜杂志

ABSTRACT

Objective To investigate the influence of preoperative biopsy protocols difference on the material amount and operation time of patients with gastric cancer for early stage underwent ESD. Methods 60 patients with gastric cancer for early stage underwent ESD were chosen from June 2013 to June 2016 and randomly divided into A group (30 patients) with multiple times and points biopsies and B group (30 patients) with targeted biopsy before surgery; the biopsy number, the total number of specimens, the postoperative pathological coincidence rate and the ESD operation time of the two groups were compared. Results The biopsy number and the total number of specimens of B group were significant shorter than that in A group (P < 0.05). The postoperative pathological coincidence rate of B group were significant higher than that in A group (P < 0.05). There was no significant difference in the time of resection range determined, labeling, submucosal injection and specimen resection handling between the two groups (P > 0.05). The time of mucous membrane dissection, hemostasis and wound handling of B group were significant shorter than that in A group (P < 0.05). Conclusion Compared with multiple times and points biopsies, targeted biopsy before surgery on patients with gastric cancer for early stage underwent ESD can efficiently reduce the trauma degree, improve the biopsy accuracy and be helpful to shorten the operation time.