A retrospective study of antiepileptic drugs, etiology and seizure patterns in hospitalized patients with epilepsy / 中国神经精神疾病杂志
Chinese Journal of Nervous and Mental Diseases
;
(12): 266-271, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-703167
ABSTRACT
Objective The aim of this study was to investigate and analyze the etiology, seizure type and anti-epileptic drugs (AEDs) utilization of in-patients with epilepsy Methods The study included 5563 cases in-patients with epilepsy. The etiology and seizure type and the date of type, quantity of AEDs in-patient department were collected and their usage frequency were analyzed statistically. Results The most common etiology of epilepsy was traumatic brain injury(13.64%), followed by hippocampal sclerosis (11.52%), stroke (5.24%), nervous system infection (4.98%), perinatal injury ( 5 . 28 % ) and undefined etiology ( 40 . 80 % ) . The most common seizure type was partial seizures (45.43% ). The AEDs of carbamazepine and valproate were the most common used drugs in the clinical and their average usage frequency were 36.88% and 30.80%, respectively. The newer AEDs of Lamotrigine and Levetiracetam were used more frequently. The use of Lamotrigine increased from 16.16% to 28.44% and the Levetiracetam from 0.61% to 20.87% whereas the use of Oxcarbazepine and Topiramate remained a stable level of 15.07% and 9.42%. Conclusion The etiology of epilepsy is complicated and the seizure type of epilepsy was diverse. Among a great variety of anti-epileptic drugs, the newanti-epileptic drugs are being increasingly used.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Etiology study
/
Observational study
Language:
Chinese
Journal:
Chinese Journal of Nervous and Mental Diseases
Year:
2018
Type:
Article
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