Meta-analysis for Vitamins Preventing Contrast Induced Nephropathy in Patients After Coronary Angiography / 中国循环杂志
Chinese Circulation Journal
;
(12): 181-186, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-703839
ABSTRACT
Objective:
To evaluate the effects for vitamins preventing contrast induced nephropathy (CIN) in patients after coronary angiography (CAG) by Meta-analysis.Methods:
We searched PubMed, Medline, Cochrane library central register of controlled trials and ClinicalTrails. gov from the database establishment to 2016-12 for CIN related references. According to enrollment and elimination standards, we chose eligible randomize control trail (RCT), extracted data and conducted a Meta-analysis using RevMan 5.3 statistical software.Results:
A total of 11 RCTs with 1810 patients were enrolled which included in 2 groups Vitamins group, n=951 and Placebo group, n=859. The average age of patients was (60-73) years and the male was (45.9-92.2) %. Meta-analysis showed that CIN occurrence rate in Vitamins group was lower than Placebo group (RR=0.54, 95% CI 0.39-0.73); compared with Placebo group, the incidence of CIN was decreased by 46% in Vitamins group. Using Vitamin C could decrease CIN occurrence rate (RR=0.58, 95% CI 0.37-0.90); compared with Placebo group, the incidence of CIN was decreased by 42% for using Vitamin C.Conclusion:
Vitamins can reduce 46% incidence of CIN and Vitamin C may reduce 42% incidence of CIN in patients after CAG.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Controlled clinical trial
/
Practice guideline
/
Systematic reviews
Language:
Chinese
Journal:
Chinese Circulation Journal
Year:
2018
Type:
Article
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