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Safety and Efficacy of Chemical Ablation With Anhydrous Alcohol Combined With Gelatin Sponge for Patients With Hypertrophic Obstructive Cardiomyopathy / 中国循环杂志
Chinese Circulation Journal ; (12): 576-579, 2018.
Article in Chinese | WPRIM | ID: wpr-703899
ABSTRACT

Objectives:

To analyze the safety and efficacy of chemical ablation of anhydrous alcohol combined with gelatin sponge for patients with hypertrophic obstructive cardiomyopathy (HOCM).

Methods:

The clinical data of 7 HOCM patients, who underwent chemical ablation with anhydrous alcohol and gelatin sponge in Fuwai Hospital from May 2017 to December 2017, were analyzed.

Results:

There were 5 males and 2 females, with a median age of 56 years (range, 43-67 years), the mean interventricular septum thickness was (19.6 ± 4.8) mm, the number of ablated septal branch was 1-2, the amount of used anhydrous alcohol was 1.4 (1.0-2.0) ml, the amount of applied gelatin sponge was 0.5 (0.1-1.3) ml. After procedure, the left ventricular outflow tract pressure was significantly decreased ([31.6 ± 12.6] mmHg vs [86.4 ± 20.7] mmHg, P<0.001), NYHA cardiac function was significantly improved (1.4 ± 0.5 vs 2.7 ± 0.8, P <0.05), no relevant complications occurred.

Conclusions:

Chemical ablation with anhydrous alcohol and gelatin sponge is safe and effective for patients with hypertrophic obstructive cardiomyopathy.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Circulation Journal Year: 2018 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Circulation Journal Year: 2018 Type: Article