Advances in self-assemblied DNA nanocages as drug delivery systems / 中国药科大学学报
Journal of China Pharmaceutical University
; (6): 663-669, 2017.
Article
in Zh
| WPRIM
| ID: wpr-704300
Responsible library:
WPRO
ABSTRACT
DNA nanocages are nanoscale three-dimensional polyhedral structures formed by self-assembled oligonucleotide strands by base pairing.DNA nanocages,especially the tetrahedron DNA nanocages,were proved to be potential nanocarriers for drug delivery,due to their good stablility,high compatibility,intracellular ablility and hollow cavity for modification and drug loading..In this paper,we reviewed the structural characteristics,synthetic methods and targeted modification of DNA nanocages,as well as their development and application in drug carriers,biological imaging,in vitro diagnosis and materials science.
Full text:
1
Index:
WPRIM
Language:
Zh
Journal:
Journal of China Pharmaceutical University
Year:
2017
Type:
Article