Preparation and Quality Evaluation of Formononetin Inclusion Compound Liposome / 中国药房
China Pharmacy
;
(12): 303-306, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-704572
ABSTRACT
OBJECTIVE:
To prepare Formononetin (FMN) inclusion compound liposome and evaluate its quality.METHODS:
FMN inclusion compound liposome was prepared by film dispersion method. The morphology, particle size, Zeta potential, encapsulation efficiency and in vitro release properties were studied.RESULTS:
The particle size, Zeta potential and encapsulation efficiency of prepared FMN inclusion compound liposome were (255. 34 ± 12. 87) nm, (25. 32 ± 3. 51) mV, (81. 63 ± 0. 79)%, respectively (n=3). The 24 h accumulative release rate of prepared FMN inclusion compound liposome was 56. 12%.CONCLUSIONS:
FMN inclusion compound liposome with good sustained-release effect is prepared successfully and in line with related quality standard.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2018
Type:
Article
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