Optimization of the Extraction Technology of Total Flavonoids from the Roots and Stems of Angelica sinensis / 中国药房
China Pharmacy
;
(12): 364-368, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-704586
ABSTRACT
OBJECTIVE:
To optimize reflux extraction technology of total flavonoids from the roots and stems of Angelica sinensis.METHODS:
The reflux extraction technology of total flavonoids from the roots and stems of A. sinensis was optimized by Box-Behnken design-response methodology based on single factor test using volume fraction of extraction solvent ethanol, solide-liquid ration, extraction time, extraction times as investigation factors, the content of total flavonoids in extract as evaluation index.RESULTS:
The optimal extraction technology of total flavonoids from the roots and stems of A. sinensis was that volume fractions of ethanol were 70% and 50%; solid-liquid ratios were 1 40 and 1 30; extraction time were 1. 3 h and 1. 7 h; The number of extraction times is two times. In verification test, the contents of total flavonoids were 7. 253 6, 25. 144 1 mg/g (RSD= 1. 57%, 1. 49%, n = 3); relative errors of those to predicted value (6. 942 8, 25. 703 5 mg/g) were 4. 28%, 2. 24%.CONCLUSIONS:
Optimized extraction technology for total flavonoids from the roots and stems of A. sinensis is simple, reproducible and predictable.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
China Pharmacy
Year:
2018
Type:
Article
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