New Molecules in Babesia gibsoni and Their Application for Diagnosis, Vaccine Development, and Drug Discovery
The Korean Journal of Parasitology
; : 345-353, 2014.
Article
in En
| WPRIM
| ID: wpr-70518
Responsible library:
WPRO
ABSTRACT
Babesia gibsoni is an intraerythrocytic apicomplexan parasite that causes piroplasmosis in dogs. B. gibsoni infection is characterized clinically by fever, regenerative anemia, splenomegaly, and sometimes death. Since no vaccine is available, rapid and accurate diagnosis and prompt treatment of infected animals are required to control this disease. Over the past decade, several candidate molecules have been identified using biomolecular techniques in the authors' laboratory for the development of a serodiagnostic method, vaccine, and drug for B. gibsoni. This review article describes newly identified candidate molecules and their applications for diagnosis, vaccine production, and drug development of B. gibsoni.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Babesia
/
Babesiosis
/
Protozoan Vaccines
/
Drug Discovery
/
Antigens, Protozoan
/
Antiprotozoal Agents
Type of study:
Diagnostic_studies
/
Prognostic_studies
Limits:
Animals
Language:
En
Journal:
The Korean Journal of Parasitology
Year:
2014
Type:
Article